The Missed Vital Sign

The goal of The Missed Vital Sign program is to demonstrate that routine recording, quantifiable measurement, and better treatment options for menstruation can reduce the time a woman experiences heavy menstrual bleeding from 5 years to 5 months. We aim to do this without increasing unwanted surgical intervention or menstrual cycle suppression.

Thrust Area 1: A high-performance multivariate tool to identify women who have HMB at levels that would result in iron deficiency.

Thrust Area 2: Identify causal factors for HMB to inform diagnostic development and identify new, precise, non-hormonal therapeutic targets, particularly those that could be self-administered.

Thrust Area 3: Develop and validate patient stratification tools to personalize management when HMB is identified and ensure effective treatment.

Funding: Not fixed limit 

Duration: 3 years

Research Authority due date: 8.5.25

Abstract (required) due date: 16.5.25

Full proposal due date: 30.6.25