Cancer Grand Challenges

Cancer Research UK and NIH's National Cancer Institute created this Call which outlines 9 ambitious challenges, each with the potential to drive radical progress in cancer reality. Multi-disciplinary global teams are invited to submit proposals. 

• AI-human collaborations in cancer
• Cancer avoidance
• The dark proteome
• Mechanisms driving mutational signatures
• The nervous system and cancer
• Rewiring cancer cells
• TME dynamics

Funding: £20,000,000 total 

Duration: 5 years 

Research Authority due date: 11.6.25

Expression of Interest (required) due date: 18.6.25

Full propoposal due date: 23.10.25