CARE: Cutting Alzheimer’s Risk through Endocrinology

The ultimate goal of this program is to cut women’s lifetime risk of Alzheimer’s in half. CARE is focused on the intersection of neuroendocrine risks and neurodegeneration so as to identify personalized preventative strategies and treatments.  The program includes three primary thrust areas designed to achieve this overall goal, designed to stratify at-risk individuals into progressively specialized diagnostic pathways. 

Thrust Area 1: Identify high-precision female-specific neuroendocrine targets and therapies for Alzheimer’s risk reduction.

Thrust Area 2: Develop high-affinity in vivo brain imaging probes for neuroendocrine function in clinical populations and their potential therapeutic application.

Thrust Area 3: Development of predictive models that halve Alzheimer’s risk in women and their deployment as risk assessment tools for clinical use

Funding: No fixed limit 

Duration: 2 years

Research Authority due date: 7.3.25

Abstract (required) due date: 14.3.25

Full proposal due date: 8.4.25