High-throughput Discovery and Validation of Novel Signal Transducers or Small Molecules that Modulate Opioid or other Substance Use Disorder Relevant Pathways (R01)

This grant will support high-throughput screening approaches to identify novel receptors, signal transducers, or small molecules that modulate Substance Use Disorder (SUD)-relevant signal transduction pathways (dopamine, opioid, cannabinoid, nicotinic, or other appropriately justified pathway).

Applicants may also propose secondary screens and/or validation of high value identified targets.

Funding: $400,000 per year

Duration: 5 years

Research Authority due date: 5.8.21

LOI (encouraged) due date: 15.8.21

Full proposal due date: 15.9.21