Development of Medications to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3)

The National Institute on Drug Abuse (NIDA) seeks research for the discovery and development of medications to prevent and treat substance use disorders (SUDs) and overdose. Application may include preclinical or clinical research studies that will have high impact and quickly yield the necessary results to advance closer to or to FDA approval. The compounds to be evaluated can be small molecules or biologic and may focus on the development of new chemical entities, new formulations of marketed medications available for other indications, or combinations of medications.

Funding: $3,000,000 per year

Duration: 5 years

Research Authority due date: 10 days prior to submission

LOI (encouraged) due dates: 10.3.25, 11.7.25

Full proposal due dates: 10.4.25, 11.8.25