Mechanisms of Reciprocal Interactions between HIV Associated Neuroinflammation and CNS Persistence: Implications in HIV Neuropathogenesis and Cure (R01)

The goal of this grant is to examine mechanisms of reciprocal interactions between HIV-associated neuroinflammation and central nervous system (CNS) HIV persistence. In particular encouraging research focused on defining the role and mechanisms of defective proviruses, HIV proteins and/or nucleic acids in inducing inflammation, immune activation and CNS co-morbidities.

Funding: no fixed limit

Duration: 5 years

Research Authority due date: 24.9.24

LOI (encouraged) due date: 8.10.24

Full proposal due date: 8.11.24