CDMRP Tuberous Sclerosis Complex Research Program: Idea Development Award

The Idea Development Award promotes new ideas that are in the early stages of development and have the potential to yield high-impact findings and new avenues of investigation. Preliminary data should be presented. The program offers separate tracks for established and new investigators 

Focus Areas:

• Understanding and treating the features of TSC-Associated Neuropsychiatric Disorders and reducing their impact, including pharmacological and behavioral interventions.
• Strategies for preventing and eradicating tumors and cysts associated with TSC (e.g., angiomyolipomas, Subependymal Giant Cell Astrocytomas, Lymphangiolomyomatosis [LAM], etc.), including gaining a deeper mechanistic understanding of tumor microenvironment, TSC signaling and mTOR-independent pathways.
• Preventing epilepsy, improving treatment, and mitigating neurodevelopmental outcomes associated with TSC-related seizures.
• Developing, assessing, and testing emerging technologies including imaging and molecular therapeutic strategies, such as gene therapy, to improve outcomes in TSC

It is expected that 3 awards will be granted.

Funding: $500,000 total.
Duration: 3 years

Research Authority due date:  3.6.24

Pre application (required) due date: 12.6.24

Full application due date: 1.8.24