Seeking predictors of vaccine efficacy: identifying correlates of protection to support vaccine development

Wellcome and CEPI want to address the barriers currently hampering the discovery and validation of reliable correlates of protection. The aim is to support coordination and collaboration between stakeholders across vaccine development to generate these robust datasets and expand the list of correlates of protection available for vaccine development. 

This call is divided into two strands, depending on the disease pathogens studied:

Strand A for bacterial/parasitic diseases

• Invasive non-typhoidal salmonella, (iNTS),
• Shigella,
• Paratyphi A,
• Extraintestinal pathogenic E coli (ExPec),
• Group A strep, or
• Schistosomiasis.

Strand B for viral-related diseases.

• Ebola virus (non-Zaire forms),
• Lassa virus,
• Marburg virus,
• Nipah virus
• Rift Valley Fever virus.

Teams may include up to 10 partners. 

Funding: £5,000,000 total 

Duration: 3 years 

Research Authority due date: 30.1.24