Microphysiological Systems to Advance Precision Medicine for AD/ADRD Treatment and Prevention (U54)

This grant invites applications aiming to establish multi-component Alzheimer’s Disease (AD) and AD-Related Dementias (ADRD) Translational Centers for Microphysiological Systems (MPS) (AD/ADRD MPS Translational Centers).  

The overarching purpose of this Centers program is to develop 2D and 3D models of AD/ADRD as reproducible and scalable platforms that recapitulate key features of human AD/ADRD pathophysiology to be used as precision medicine research tools to investigate the complex biology of AD/ADRD and to accelerate multiple aspects of drug discovery and preclinical drug development. 

Funding: $2,500,000 per year 

Duration: 5 years

Research Authority due date: 4.1.24

LOI (encouraged) due date: 15.1.24

Full proposal due date: 15.2.24