Pathway and Pipeline Grants

The Foundation supports and promotes research that can advance understanding, treatment and prevention of progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD).

Partucular topics include: 

Pathway Grants:

– Autophagy/proteostasisSystem neuroscience (e.g., synaptic dysfunction or loss)
– Biological roles of GWAS hits
– Environmental causes and geographical clusters
– Nuclear architecture, epigenetics and transcription regulation
– Innate and adaptive immunity in tauopathies
– Mendelian families
– Validation of existing animal and human-derived preclinical models
– Sleep physiology
– Tau strains

Pipeline Grants:
– Validation of novel drug targets
– Cell replacement therapy/regenerative approaches
– Biomarker validation (diagnostic, disease progression, comorbidities)
– Prodromal and early-stage diagnostic markers
– Diagnostic platform validation (e.g., RT-QuIC)
– Proof-of-concept clinical trials
– Rehabilitation strategies for motor and nonmotor deficits
– RNA-based neuroprotection
– Symptomatic clinical drug trials
– Symptomatic clinical non-pharmacological trials

 

 

  

Funding: $100,000 total 

Duration: 2 years

 

 

 

Research Authority due date: 21.3.24