CDMRP Melanoma Research Program: Focused Program Award – Rare Melanomas

קרןUS Department of Defense
מדינהU.S.A.
סוגResearch Grants
תאריך אחרון14/09/2022
פקולטהLife Sciences, Medicine
תיאור

The goal of the Melanoma Research Program (MRP) is to prevent melanoma initiation and progression.

FPA-RM applications must describe a unifying, overarching question that will be investigated by a set of research projects that address a critical unmet need relevant to rare melanoma research and/or patient care.

Applications should include multiple (2-3), distinct research projects that are each led by individual Project Leaders and address complementary aspects of the overarching question.

 

Applicants must address at least one of the following Focus Areas.
  • Research across the entire spectrum (biology, etiology, prevention, diagnosis and detection, prognosis, treatment, and quality of life) for rare melanomas (e.g., uveal, acral, mucosal, pediatric) in patients and model organisms.
  • Identify and understand risk factor determinants for melanoma, including rare subtypes.
  • Develop prediction and surveillance tools for distinguishing patient populations at risk for second primary/recurrence and/or metastasis.
  • Understand how precursor lesions and environmental/endogenous factors influence melanomagenesis, including (but not limited to) race, sex as a biological variable, etc.
  • Develop new tools for the detection and diagnosis of melanoma, which includes easily accessible technology (beyond the dermoscope) for primary care physicians and dermatologists.
  • Identify how the tumor microenvironment (e.g., stromal, immune, microbiome) impacts tumor initiation, response to therapy, progression, recurrence, and/or dormancy.
  • Delineate the molecular pathways that influence metastatic spread, recurrence, and/or dormancy.

 

 

It is expected that two (2) award will be granted. 

 

 

Funding: $2,000,000 total

Duration: 4 years 

 

 

Research Authority due date: 7.9.22

Pre application (required) due date: 14.9.22

Full proposal due date: 5.10.22
קבצים מצורפים
DoD_Melanoma_Focused_Award_Rare_Melanomas_2022.pdf
קישורלאתר
עדכון אחרוןעדכון אחרון: 02/06/2022
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