CDMRP Tuberous Sclerosis Complex Research Program: Exploration – Hypothesis Development Award

The Exploration – Hypothesis Development Award supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in the TSC research field. The studies supported by this award mechanism are expected to lay the groundwork for future avenues of scientific investigation.

Focus Areas:

• Understanding and treating the features of TSC-Associated Neuropsychiatric Disorders (TAND) and reducing their impact, including pharmacological and behavioral interventions
• Strategies for eradicating tumors associated with TSC and TSC-associated lymphangioleiomyomatosis (LAM), including gaining a deeper mechanistic understanding of TSC signaling pathways and tumor microenvironment
• Preventing epilepsy, improving treatment, and mitigating neurodevelopmental outcomes associated with TSC-related seizures

It is expected that 6 awards will be granted. 

Funding: $150,000 total
Duration: 2 years

Research Authority due date: 23.6.22

Pre application (required) due date: 30.6.22

Full application due date: 28.7.22