Selectively Target Technology Development to Understand How Changes or Dysfunction at the Capillary, Arterioles, and Small Lymphatic Vessels Level Can Have Long-term Impact on AD/ADRD (R01)

The purpose of this grant is to solicit studies that will advance the mechanistic understanding of small vessel vascular contributions to cognitive impairment and dementia (VCID) through the development of new technologies and innovative methods that enable the imaging and/or functional assessment of the small blood and lymphatic vessels and perivascular spaces of the brain.

This program aims to facilitate the development of tools and technology to image, profile and/or mechanistically characterize CNS small blood and lymphatic vessels in Alzheimer’s Disease and Alzheimer’s Disease-Related Dementia (AD/ADRD) animal models or patient populations.

Funding: $499,000 per year 

Duration: 5 years 

Research Authority due date: 1.10.21

LOI (encouraged) due date: 8.10.21

Full proposal due date: 8.11.21