Target Advancement Program
|קרן||Michael J. Fox Foundation for Parkinson's Research|
|פקולטה||Exact Sciences, Life Sciences, Medicine|
This grant seeks applications that leverage and translate basic research in order to enable therapeutic development.
Applications should focus on studies that achieve one or more of the following goals:
• Demonstrate pathological relevance of a target by studying its altered expression, distribution, or function in PD-relevant human tissues.
• Demonstrate that modulation of the target or pathway in vivo in whole mammalian PD models using genetic or pharmacological manipulations yields outcomes predictive of clinical efficacy or relevance in human PD.
• Elucidate target or pathway biology in disease-relevant models, including defining upstream/downstream modifiers and convergence of promising target pathways.
• Replicate or further validate recently published, high-impact findings in PD biology.
Funding: $200,000 total
Duration: 18 months
Research Authority due date:
LOI (required) due date:
Full proposal due date:
|עדכון אחרון||עדכון אחרון: 19/03/2020|