(PsychENCODE: Non-coding Functional Elements in the Human Brain and their Role in the Development of Psychiatric Disorders (Collaborative U01

קרןNational Institutes of Health (NIH)
מדינהU.S.A.
סוגResearch Grants
תאריך אחרון06/06/2019
פקולטהExact Sciences, Life Sciences, Medicine, Social Sciences
תיאור

The objective of this FOA is to support research in the discovery and characterization of the full spectrum of human-specific non-coding functional genomic elements across brain regions, cell types, and developmental time periods to elucidate their role(s) in the molecular pathophysiology of mental illness. It is expected that projects under this FOA will apply unbiased genome-wide approaches, computational methods, and experimental assays to identify and characterize functional genomic elements in both healthy and diseased human brains to correlate findings with development of mental illnesses and outcomes relevant to brain function and dysfunction. Projects should work towards developing comprehensive maps of functional elements, including insulators, enhancers, promoters, silencers, transcription binding factors, non-coding RNAs (e.g., long non-coding RNAs [lncRNAs], microRNAs [miRNAs], piwi-interacting RNAs [piRNAs]), modifications to RNA, RNA spliceoforms, long-range chromatin interactions, DNA methylations, etc.

This FOA should be used when two or more collaborating sites are essential to complete the proposed research. It is required that the Research Strategy be identical across linked collaborative U01 applications, with the exception of a short section describing the specific function of each application under "elements unique to that site." For a linked set of collaborative U01 applications, each application must have its own Program Director/Principal Investigator (PD/PI) and the program must provide a mechanism for cross-site coordination

research authority due date: 1.6.17

LOI: 6.6.17

 deadline dates: July 6, 2017, June 6, 2018, June 6, 2019

funding: not specified

duration: 5 years

קבצים מצורפים
קישורלאתר
עדכון אחרוןעדכון אחרון: 24/04/2017
אוניברסיטת תל-אביב, ת.ד. 39040, תל-אביב 6997801
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