CDMRP Melanoma Research Program: Translational Research Award

קרןUS Department of Defense
מדינהU.S.A.
סוגResearch Grants
תאריך אחרון09/09/2021
פקולטהEngineering, Exact Sciences, Life Sciences, Medicine
תיאור

The goal of the Melanoma Research Program (MRP) is to prevent melanoma initiation and progression. Preliminary results and clear impact potential are required. 

 

 FY21 MRP Translational Research Award must address at least one of the ollowing Focus Areas.
  • Identify methods to decrease risk of melanoma development beyond sunscreen and protective clothing.
  • Identify and understand risk factor determinants for melanoma, including variants (e.g., uveal, acral, mucosal melanoma).
  • Identify how the tumor microenvironment (e.g., stromal, immune, microbiome) impact tumor initiation, response to therapy, progression, and dormancy.
  • Understand how precursor lesions and endogenous host factors may lead to melanomagenesis.
  • Develop new decision-making tools for the detection and diagnosis of melanoma that includes easily accessible technology (beyond the dermoscope) for primary care physicians and dermatologists.
  • Develop prediction and surveillance tools for distinguishing patient at risk for recurrence and/or metastasis. Identify biological determinants to differentiate patient populations.
  • Understand mechanisms that underlie metastatic spread to different (regional/nodal) sites or the different distant sites of metastasis from acral, mucosal, and uveal melanomas. 
  • Delineate the molecular pathways, tumor microenvironment, immune response that influence metastatic spread, recurrence, and/or dormancy.

 

The MRP strongly encourages the use of Department of Defense (DoD)/Department of Veterans Affairs (VA) databases and participation by DoD/VA investigators.

It is expected that four (4) awards will be granted. 

 

Funding: $600,000 total ($700,000 for collaborative applications. Clinical and basic science partnerships are encouraged. Multi institutional applications are highly encouraged) 

Duration: 3 years 

 

 

Research Authority due date: 28.7.21 1.9.21

Pre applicaton (required) due date: 4.8.21 9.9.21

Full proposal due date: 26.8.21 28.9.21
קבצים מצורפים
DoD_Melanoma_Translational_Research_Award_2021.pdfDoD_Melanoma_Translational_Research_Award_2021_amended_dates.pdf
קישורלאתר
עדכון אחרוןעדכון אחרון: 22/07/2021
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